Avoid intake of methotrexate, phenytoin bisphosphonates such as alendronate, cyclosporine, methotrexate, sulfonamides because the risk of their side effects may be increased by feldene.

Information about Feldene.

NSAIDsincluding FELDENEmay increase the risk of bleeding eventsCo-morbid conditions such as coagulation disordersconcomitant use of warfarinother anticoagulantsantiplatelet agentse.gaspirinserotonin reuptake inhibitorsSSRIsand serotonin norepinephrine reuptake inhibitorsSNRIsmay increase this riskMonitor these patients for signs of bleedingsee DRUG INTERACTIONS

If the patient has developed SJS or TEN with the use of piroxicampiroxicam must not be re-started in this patient at any time.

Before taking piroxicamtell your doctor if you are allergic to any drugsor if you have:

Carefully consider the potential benefits and risks of FELDENE and other treatment options before deciding to use FELDENEUse the lowest effective dosage for the shortest duration consistent with individual patient treatment goalssee WARNINGS AND PRECAUTIONS

Before taking this medicationtell your doctor or pharmacist your medical historyespecially ofasthmaincluding a history of worsening breathing after taking aspirin or other NSAIDsblood disorderssuch as anemiableeding/clotting problemsgrowths in the nosenasal polypsheart diseasesuch as previous heart attackhigh blood pressureliver diseasestrokethroat/stomach/intestinal problemssuch as bleedingheartburnulcers

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before using risedronate, tell your doctor if you also use aspirin or other nsaids non-steroidal anti-inflammatory drugs such as celecoxib celebrex , diclofenac voltaren , diflunisal dolobid , ibuprofen motrin, advil , indomethacin, ketoprofen orudis , ketorolac toradol , naproxen aleve, naprosyn , piroxicam feldene , and others.