The following sections describe in detail the possibly negative interactions that can occur when zofran is joined with the drugs.

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Certain drugs may increase the risk of serious side effects when used with ZofranZuplenz or generic ondansetron.

Your heart function may need to be tested with an electrocardiogramECG or EKGon a regular basisDo not miss any follow-up visits to your doctor.

There is no specific antidote for ondansetron overdosePatients should be managed with appropriate supportive therapy.

Hypersensitivity reactionsincluding anaphylaxis and bronchospasmhave been reported in patients who have exhibited hypersensitivity to other selective 5-HT 3 receptor antagonistsIf hypersensitivity reactions occurdiscontinue use of ZOFRANtreat promptly per standard of care and monitor until signs and symptoms resolvesee CONTRAINDICATIONS

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