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Nimodipine inhibits calcium ion transfer into these cells and thus inhibits contractions of vascular smooth muscle.

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Safety and effectiveness in children have not been established. Clinical studies of nimodipine did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. Symptoms of overdosage would be expected to be related to cardiovascular effects such as excessive peripheral vasodilation with marked systemic hypotension.

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